Table 7.
Cohen’s d effect sizes comparing Naltrexone versus Placebo and Combined Behavioral Intervention (CBI) versus Medication Management (MM) subscale and total WHOQOL-BREF summary scores with week-26 and week-52 timepoints
| Naltrexone versus Placebo | CBI versus MM | |
|---|---|---|
| Physical Health Subscale, Week 26 | 0.06 | 0.06 |
| Physical Health Subscale, Week 52 | 0.06 | 0.14 |
| Psychological Health Subscale, Week 26 | 0.03 | 0.03 |
| Psychological Health Subscale, Week 52 | 0.10 | 0.05 |
| Social Relationships Subscale, Week 26 | 0.04 | 0.08 |
| Social Relationships Subscale, Week 52 | 0.13 | 0.05 |
| Environment Subscale, Week 26 | 0.09 | 0.08 |
| Environment Subscale, Week 52 | 0.11 | 0.01 |
| Total Summary Score, Week 26 | 0.07 | <0.01 |
| Total Summary Score, Week 52 | 0.11 | 0.07 |
Note. CBI = Combined Behavioral Intervention, MM = Medication Management