Table 3.
Effects of voluntary running on hippocampal synaptic plasticity in animal models of neurological disorders
| Animal model | Animal age | Running period | Area analyzed | Effect of running | Reference |
| FASD | 8 weeks old/ Rat | 10 days | DG | Rescued deficit in LTP | Christie et al., 2005 |
| TBI | Not reported | ||||
| Stroke | Not reported | ||||
| AD | 7 months old/ Mouse/ | ||||
| 3xTg-AD | 6 months | CA1 | Rescued deficit in LTP | García-Mesa et al., 2011 | |
| PD | Not reported | ||||
| HD | Not reported |
Abbreviations: AD, Alzheimer’s disease; CA, Cornu Ammonis; DG, dentate gyrus; FASD, fetal alcohol spectrum disorders; HD, Huntington’s disease; LTP, long-term potentiation; PD, Parkinson’s disease; TBI, traumatic brain injury.