Table 1.
Quantification of relative percentage of microglia interacting with the 3- and 6-weeks old newborn neurons in the granule cell layer (GCL), inner molecular layer (iML), and middle/outer molecular layer (mML/oML) in non-stimulated controls (NSC) and after status epilepticus (SE). Data are presented as mean ± SEM,n = 3–5 animals for each group (10–15 GFP+ newborn neurons per animal).* - significant difference between NSC and SE groups in relative percentage of ramified microglia interacting with the proximal dendrites of 3-weeks old neurons in iML by 2-way ANOVA (F (2,12) = 4.080, p = 0.04)
| Groups | % microglia interacting in dentate gyrus | |||||
| Ramified | Intermediate | |||||
| GCL | iML | mML/oML | GCL | iML | mML/oML | |
| 3 w-old neurons (NSC) | 14.4 ± 5.3 | 22.3 ± 1.6 | 63.2 ± 6.7 | 10.7 ± 4.2 | 32.3 ± 5.0 | 57.0 ± 7.7 |
| 3 w-old neurons (SE)* | 11.4 ± 9.0 | 50.4 ± 16.5 | 38.2 ± 9.8 | 5.8 ± 2.6 | 32.0 ± 6.2 | 62.2 ± 8.3 |
| 6 w-old neurons (NSC) | 25.8 ± 19.7 | 47.1 ± 16.9 | 27.1 ± 11.5 | 2.1 ± 2.1 | 34.3 ± 12.4 | 63.7 ± 12.8 |
| 6 w-old neurons (SE) | 3.3 ± 3.3 | 48.9 ± 25.8 | 47.8 ± 24.8 | 11.3 ± 5.9 | 56.0 ± 22.0 | 32.7 ± 16.4 |