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. 2017 Nov 9;3(1):43–59. doi: 10.3233/BPL-160036

Table 2.

Differentially expressed AHN-related MicroRNAs in epilepsy

Expression during Expression during Predicted Biological References
acute stage chronic stage consequence
miR-184 Up Up Increased proliferation [121, 122]
miR-106b/25 cluster Up Up Increased proliferation and neuronal differentiation [123, 132, 157]
miR-34a Up Up Increased proliferation, [123, 124, 133]
Increased apoptosis
miR-124 Up Up Increased neuronal differentiation, [82, 131]
Decreased apoptosis
miR-137 Up Up Increased proliferation, [82, 129]
Decreased apoptosis
miR-9 Down Up Dynamic changes in proliferation and differentiation [129, 130]
Let-7b Down Down Increased proliferation, Decreased differentiation [129]
miR-26b Up Up Increased neuronal differentiation [82, 164]
miR-145 Up/Down Up/Down Changes in neuronal differentiation [123, 130, 165]
miR-125b Up Up Increased neuronal differentiation [132, 166]
miR-19 Up Up Increased migration [123]
miR-379/410 cluster Up Up Increased migration [82, 122, 132]
miR-138 Down Down Increased spinogenesis [82, 132]
miR-134 Up Up Decreased spinogenesis [131]
miR-132 Up Up Increased spinogenesis [123, 132, 167]

Overview of differentially expressed microRNAs in epilepsy known to be involved in neurogenesis, and their (predicted) biological consequence.