Table 5.
Interaction between APOE and LPL SNPs and dietary factors on total cholesterol in the CaPS
| Interaction between rs320 at LPL *dietary factors on Total Cholesterol | ||
|---|---|---|
| Interaction between SNP rs320* fat energy % intake | Interaction between SNP rs320* protein energy % intake | Interaction between SNP rs320* carbohydrate energy % intake |
| 0.01 (0.01) 0.48 |
− 0.01 (0.03) 0.57 |
− 0.004 (0.01) 0.64 |
| Interaction between rs328 at LPL *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs328* fat energy % intake | Interaction between SNP rs328* protein energy % intake | Interaction between SNP rs328* carbohydrate energy % intake |
| − 0.01 (0.01) 0.58 |
−0.04 (0.03) 0.17 |
0.01 (0.01) 0.29 |
| Interaction between rs405509 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs405509* fat energy % intake | Interaction between SNP rs405509* protein energy % intake | Interaction between SNP rs405509* carbohydrate energy % intake |
| 0.03 (0.01) 0.11 |
−0.04 (0.04) 0.52 |
−0.02 (0.01) 0.31 |
| Interaction between rs769450 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs769450* fat energy % intake | Interaction between SNP rs769450* protein energy % intake | Interaction between SNP rs769450* carbohydrate energy % intake |
| −0.01 (0.01) 0.10 |
0.05 (0.02) 0.04 |
0.01 (0.01) 0.42 |
| Interaction between rs439401 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs439401* fat energy % intake | Interaction between SNP rs439401* protein energy % intake | Interaction between SNP rs439401* carbohydrate energy % intake |
| −0.003 (0.01) 0.77 |
−0.01 (0.03) 0.68 |
0.004 (0.01) 0.65 |
| Interaction between rs445925 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs445925* fat energy % intake | Interaction between SNP rs445925* protein energy % intake | Interaction between SNP rs445925* carbohydrate energy % intake |
| −0.0003 (0.01) 0.97 |
−0.02 (0.03) 0.55 |
0.002 (0.01) 0.87 |
| Interaction between rs405697 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs405697* fat energy % intake | Interaction between SNP rs405697* protein energy % intake | Interaction between SNP rs405697* carbohydrate energy % intake |
| 0.01 (0.01) 0.51 |
−0.03 (0.03) 0.24 |
−0.002 (0.01) 0.84 |
| Interaction between rs1160985 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs1160985* fat energy % intake | Interaction between SNP rs1160985* protein energy % intake | Interaction between SNP rs1160985* carbohydrate energy % intake |
| −0.01 (0.01) 0.13 |
−0.004 (0.03) 0.19 |
0.01 (0.01) 0.43 |
| Interaction between rs1064725 at APOE *dietary factors on Total Cholesterol | ||
| Interaction between SNP rs1064725* fat energy % intake | Interaction between SNP rs1064725* protein energy % intake | Interaction between SNP rs1064725* carbohydrate energy % intake |
| −0.01 (0.03) 0.66 |
0.05 (0.11) 0.62 |
0.01 (0.03) 0.74 |
| Interaction between APOE (E2,E3, and E4)*dietary factors on Total Cholesterol | ||
| Interaction between SNP APOE (E2, E3, and E4)* fat energy % intake | Interaction between SNP APOE (E2, E3, and E4)* protein energy % intake | Interaction between SNP APOE (E2, E3, and E4)* carbohydrate energy % intake |
| −0.02 (0.02) 0.038 |
0.02 (0.04) 0.83 |
0.01 (0.01) 0.08 |
Values represented β regression coefficients (± S.E), and Pinteraction
P values were obtained by using a general linear model adjusted for age, sex, body mass index, country and total energy intake, wherever appropriate
Bonferroni corrected P value < 0.001 was considered statistically significant