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Reverse transcription-quantitative polymerase chain reaction in MCF-7/MDR and MCF-7 cells verified the mRNA expression of the 9 hub genes identified in the protein-protein interaction network. *P<0.05 and **P<0.01 vs. MCF-7 cells. MDR, multidrug resistance; BDNF, brain-derived neurotrophic factor; PLCB, phospholipase C β; ACTC1, actin α cardiac muscle 1; NOS3, nitric oxide synthase 3; CCND1, cyclin D1; NPY, neuropeptide Y; PAX6, paired box 6.
