Table II.
Top 11 microRNAs targeting collagen type IV α1 mRNA predicted by microRNA-mRNA interactions, and their drug resistance-associated functions in cancer.
| miRNA-mRNA prediction tools | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Author, year | miRNA (hsa-) | A | B | C | D | E | F | G | H | I | Drug resistance-related functions of miRNAs in cancers | (Refs.) |
| Okamoto et al, 2013 | miR-29b-3p | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | (45) |
| Liu et al, 2016 | miR-124-3p | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | (46) |
| Chen et al, 2017 | miR-148a-3p | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | (47) |
| Zhong et al, 2013 | miR-29a-3p | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | (48) |
| Chen et al, 2017 | miR-152-3p | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | (47) |
| Sui et al, 2015 | miR-148b-3p | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | Drug resistance-related | (49) |
| Tong et al, 2011 | miR-506-3p | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | Drug resistance-related | (50) |
| – | miR-628-5p | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | – |
| Zhang et al, 2013 | miR-29c-3p | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | Drug resistance-related | (51) |
| – | miR-767-5p | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Drug resistance-related | – |
| – | miR-637 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | Drug resistance-related | – |
A, miRWalk; B, miRanda; C, miRDB; D, miRNAMap; E, Pictar2; F, PITA; G, RNA22; H, RNAhybrid; I, TargetScan; miRNA/miR, microRNA.