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(A) Reverse transcription-quantitative polymerase chain reaction and (B and C) immunohistochemistry analyses revealed enhanced p-ATM expression in prostate cancer tissues from patients with CRPC compared with those with HDPC. ***P<0.01 vs. HDPC. Magnification, ×40. ATM, ataxia telangiectasia mutated kinase; CRPC, castration-resistant prostate cancer; HDPC, hormone-dependent prostate cancer; p-, phosphorylated.
