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miR-34a and p53 expression levels in IM treated keloid fibroblasts. miR-34a expression was increased in a time-dependent manner following 1 µmol IM treatment in keloid fibroblasts parallel to p53 expression levels. ***P<0.001 vs. control (untreated) keloid cells (as indicated). IM, Ingenol Mebutate; miR, microRNA.
