Table I.
Group | T0 | T1 | T2 | T3 |
---|---|---|---|---|
NS | 349.7500±34.70339 | 276.1667±18.21378 | 321.2083±33.45647 | 347.6250±39.13430 |
NIR | 340.2500±69.56634 | 202.0417±17.91188a | 242.2500±37.09144a | 234.1250±8.93833a |
NIRA | 341.6667±43.32974 | 188.7083±28.02294a | 298.6667±48.61443b | 357.2500±57.97111b |
DS | 379.5000±38.02828 | 241.8833±21.36227a–c | 298.6667±48.61443a,b | 291.9583±54.47715b |
DIR | 331.3333±67.44992 | 161.8917±39.01699a,b,d | 192.2500±22.51777a–d | 168.7917±22.67235a–d |
DIRA | 396.9167±100.8507 | 159.7083±37.90957a,d,e | 236.3333±28.56075a,c,d,e | 217.2500±42.53528a,c,d,e |
T0-T3 represent the following time points: Baseline, the end of ischemia, 120 min, and 240 min following reperfusion, respectively. PaO2/FiO2, partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2). Results are expressed as the mean ± standard deviation (n=6).
P<0.05 vs. NS group
P<0.05 vs. NIR group
P<0.05 vs. NIRA group
P<0.05 vs. DS group
P<0.05 vs. DIR group. DIR, diabetic I/R group, in which the lung was subjected to 90 min of ischemia and 4 h of reperfusion; DIRA, diabetic I/R + gAPN group, in which 10 µg gAPN was injected 10 min prior reperfusion; DS, diabetic sham group, in which the left lung hilum was not clamped; NIR, I/R, in which the lung was subjected to 90 min of ischemia and 4 h of reperfusion; NIRA, I/R + gAPN, in which 10 µg gAPN was injected 10 min prior to reperfusion; NS, Sham group, in which the left lung hilum was not clamped. I/R, ischemia/reperfusion; gAPN, adiponectin globular domain.