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. 2018 Mar 14;17(5):7191–7201. doi: 10.3892/mmr.2018.8748

Table I.

Effects of gAPN on pulmonary oxygenation.

Group T0 T1 T2 T3
NS 349.7500±34.70339 276.1667±18.21378 321.2083±33.45647 347.6250±39.13430
NIR 340.2500±69.56634 202.0417±17.91188a 242.2500±37.09144a 234.1250±8.93833a
NIRA 341.6667±43.32974 188.7083±28.02294a 298.6667±48.61443b 357.2500±57.97111b
DS 379.5000±38.02828 241.8833±21.36227ac 298.6667±48.61443a,b 291.9583±54.47715b
DIR 331.3333±67.44992 161.8917±39.01699a,b,d 192.2500±22.51777ad 168.7917±22.67235ad
DIRA 396.9167±100.8507 159.7083±37.90957a,d,e 236.3333±28.56075a,c,d,e 217.2500±42.53528a,c,d,e

T0-T3 represent the following time points: Baseline, the end of ischemia, 120 min, and 240 min following reperfusion, respectively. PaO2/FiO2, partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2). Results are expressed as the mean ± standard deviation (n=6).

a

P<0.05 vs. NS group

b

P<0.05 vs. NIR group

c

P<0.05 vs. NIRA group

d

P<0.05 vs. DS group

e

P<0.05 vs. DIR group. DIR, diabetic I/R group, in which the lung was subjected to 90 min of ischemia and 4 h of reperfusion; DIRA, diabetic I/R + gAPN group, in which 10 µg gAPN was injected 10 min prior reperfusion; DS, diabetic sham group, in which the left lung hilum was not clamped; NIR, I/R, in which the lung was subjected to 90 min of ischemia and 4 h of reperfusion; NIRA, I/R + gAPN, in which 10 µg gAPN was injected 10 min prior to reperfusion; NS, Sham group, in which the left lung hilum was not clamped. I/R, ischemia/reperfusion; gAPN, adiponectin globular domain.