Table 1.
Summary of demographic, clinical, and virologic data on ZIKV-exposed and control animals
| Animal | NHP# | Species | Age (years), sex | Viremia | Peak viremia (log10 FFU/mL) | Viruria | Salivary secretion | ZIKV PRNT80 |
|---|---|---|---|---|---|---|---|---|
| 1 | 5759 | Saimiri boliviensis | 3, F | + | 4.91 | + | + | 1:80 at 28 dpi |
| 2 | 5779 | S. boliviensis | 3, F | − | − | − | +* | 1:80 at 28 dpi |
| 3 | 5371 | Saimiri sciureus | 5, F | − | − | − | − | < 1:20 at 28 dpi |
| 4 | 5584 | S. sciureus | 4, F | + | 5.05 | + | + | 1:160 at 28 dpi |
| 5—control | 5834 | S. sciureus | 3, F | − | − | − | − | < 1:20 at 28 dpi |
| 6—control | 5817 | S. sciureus | 3, F | − | − | − | − | < 1:20 at 28 dpi |
| 7 | 85864 | Aotus nancymaae | 6, F | − | − | − | − | < 1:40 at 7 dpi |
| 8 | 86480 | A. nancymaae | 16, M | − | − | − | − | < 1:40 at 7 dpi |
| 9 | 85939 | A. nancymaae | 14, M | + | 2.55 | − | − | 1:320 at 14 dpi |
| 10 | 86101 | A. nancymaae | 11, F | + | 0.94 | − | − | 1:160 at 14 dpi |
dpi = days postinoculation; FFU = focus-forming units; PRNT = plaque reduction neutralization test; ZIKV = Zika virus.
*
Salivary secretion of 1.92 log10 FFU/mL at 22 dpi.