Table 1.
Comparison of demographic and clinical features of EVD in adult and elderly patients in Guinea
| Variables | Number of patients | Adults (N = 2,004) | Elderly (N = 309) | P value |
|---|---|---|---|---|
| Sociodemographics | ||||
| Median age, years (IQR) | – | 35 (23–44) | 65 (60–70) | < 0.001* |
| Gender (male), n (%) | 1,128 | 986 (49.2) | 142 (45.8) | 0.14 |
| Residence, n (%) | ||||
| Macenta | 490 | 418 (20.9) | 72 (23.2) | – |
| Conakry | 390 | 360 (18.0) | 30 (9.7) | – |
| Forecariah | 270 | 231 (11.5) | 39 (12.6) | – |
| Gueckedou | 179 | 156 (7.8) | 23 (7.4) | – |
| Coyah | 150 | 128 (6.4) | 22 (7.1) | – |
| N’Zerekore | 145 | 121 (6.0) | 24 (7.7) | – |
| Kerouane | 113 | 100 (5.0) | 13 (4.2) | – |
| Kissidougou | 53 | 40 (2.0) | 13 (4.2) | – |
| Kindia | 52 | 45 (2.2) | 7 (2.3) | – |
| Profession, n (%) | ||||
| Housewife | 309 | 253 (19.1) | 56 (22.4) | 0.13 |
| Farmer | 141 | 119 (9.0) | 22 (8.8) | 0.51 |
| Health-care worker | 98 | 88 (6.6) | 10 (4.0) | 0.69 |
| Business person | 45 | 43 (3.2) | 2 (0.8) | 0.01 |
| Religious leader | 2 | 2 (0.2) | 0 (0) | 0.70 |
| Transporter | 20 | 19 (1.4) | 1 (0.4) | 0.14 |
| Traditional healer | 2 | 2 (0.6) | 0 (0) | 0.25 |
| Risk factor for exposure to EVD, n (%) | ||||
| History of contact with suspected or confirmed cases | 513 | 457 (79.5) | 56 (86.2) | 0.13 |
| History of traveling to hot spot areas | 104 | 96 (19.7) | 8 (14.5) | 0.23 |
| History of attending funeral | 213 | 184 (37.8) | 29 (50.9) | 0.039 |
| Symptoms, n (%) | ||||
| Fever | 1,302 | 1,152 (92.2) | 150 (91.5) | 0.41 |
| Fatigue | 1,233 | 1,077 (91.1) | 156 (94.5) | 0.08 |
| Anorexia | 1,099 | 804 (81.7) | 93 (80.9) | 0.45 |
| Vomiting | 835 | 751 (78.4) | 84 (73.7) | 0.15 |
| Diarrhea | 793 | 701 (77.0) | 92 (76.0) | 0.44 |
| Muscle pain | 897 | 503 (61.5) | 71 (68.9) | 0.86 |
| Joint pain | 800 | 403 (56.0) | 45 (56.3) | 0.53 |
| Headache | 448 | 658 (74.8) | 76 (74.5) | 0.51 |
| Hiccups | 140 | 129 (23.6) | 11 (18.6) | 0.24 |
| Abdominal pain | 507 | 452 (59.9) | 55 (59.1) | 0.48 |
| Difficulty in swallowing | 49 | 43 (16.3) | 6 (13.3) | 0.09 |
| Chest pain | 138 | 124 (36.9) | 14 (29.8) | 0.21 |
| Cough | 124 | 107 (32.6) | 17 (34.0) | 0.48 |
| Difficulty in breathing | 86 | 78 (25.2) | 8 (16.7) | 0.13 |
| Sore throat | 81 | 74 (24.9) | 7 (14.9) | 0.40 |
| Unexplained bleeding | 190 | 167 (25.9) | 23 (29.5) | 0.28 |
| Gum bleeding | 6 | 6 (1.5) | 0 (0.0) | 0.54 |
| Hematemesis | 11 | 11 (2.7) | 0 (0.0) | 0.30 |
| Jaundice | 17 | 16 (9.6) | 1 (4.2) | 0.33 |
| Conjunctivitis | 88 | 85 (28.9) | 3 (7.9) | 0.03 |
| Comorbodity: malaria, n (%) | 116 | 98 (25.2) | 18 (30) | 0.36 |
| Case fatality rate, n (%) | 1,574 | 1,324 (66.1) | 250 (80.6) | < 0.001 |
| Other parameters, median in days (IQR) | ||||
| Time between onset and admission | 4 (3–6) | 5 (3–7) | < 0.001* | |
| Length of hospitalization | 8 (4–13) | 6 (3–11) | < 0.001* | |
| Survival time | 11 (7–16) | 9 (6–15) | 0.007* |
EVD = Ebola virus disease; IQR = interquartile range; N = the number of patients in each comparison group; n = the number of patients having a specific demographic or clinical feature.
*
Continuous variables.