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. 2017 Oct 23;98(1):57–66. doi: 10.4269/ajtmh.17-0437

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© The American Society of Tropical Medicine and Hygiene

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Figure 6. — Immunoglobulin G (IgG) reactivity is lower to Plasmodium falciparum proteins with human orthologs. (A) Mean IgG reactivities to P. falciparum proteins with (N = 320) or without (N = 767) human orthologs. Vertical bars represent standard deviation from mean. (B) Mean IgG reactivities to P. falciparum proteins with (N = 320) or without (N = 767) human orthologs stratified by age. All data are normalized to mean IgG reactivity of U.S. adults. Comparisons in (A) were made using a linear model and in (B) a linear mixed-effects model. ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05, ns = not significant.