Table 2.
Geographical distribution of pfmdr1 and pfcrt mutants based on the country of origin
| Nation | Cases | pfmdr1 | pfcrt | |||
|---|---|---|---|---|---|---|
| N86Y | C72S | M74I | N75K | K76T | ||
| Angola | 139 | 20 | 1 | 10 | 3 | 53 |
| Equatorial Guinea | 82 | 35 | 1 | 4 | 1 | 16 |
| Nigeria | 46 | 6 | 1 | 1 | 1 | 17 |
| Cameroon | 26 | 7 | 0 | 1 | 1 | 5 |
| Ghana | 22 | 0 | 0 | 1 | 1 | 1 |
| Democratic Republic of the Congo | 18 | 4 | 0 | 0 | 0 | 3 |
| Republic of Congo | 16 | 2 | 0 | 0 | 0 | 8 |
| Zambia | 16 | 0 | 0 | 0 | 0 | 0 |
| Guinea | 10 | 2 | 0 | 1 | 0 | 3 |
| Ivory Coast | 8 | 1 | 0 | 1 | 1 | 1 |
| Gabon | 7 | 3 | 0 | 1 | 0 | 3 |
| Malawi | 7 | 0 | 0 | 0 | 0 | 0 |
| Mozambique | 5 | 0 | 0 | 0 | 0 | 0 |
| Ethiopia | 4 | 2 | 0 | 0 | 0 | 3 |
| Benin | 4 | 0 | 0 | 1 | 0 | 3 |
| Uganda | 4 | 0 | 0 | 2 | 0 | 0 |
| Sierra Leone | 3 | 1 | 0 | 0 | 0 | 1 |
| Tanzania | 3 | 0 | 0 | 0 | 0 | 0 |
| Togo | 2 | 0 | 0 | 0 | 0 | 0 |
| Kenya | 2 | 0 | 0 | 0 | 0 | 0 |
| Madagascar | 2 | 2 | 0 | 0 | 0 | 0 |
| Niger | 2 | 0 | 0 | 0 | 0 | 0 |
| Chad | 2 | 1 | 0 | 0 | 0 | 1 |
| Algeria | 1 | 0 | 0 | 0 | 0 | 1 |
| Unknown* | 1 | 0 | 0 | 1 | 0 | 1 |
| South Sudan | 1 | 0 | 0 | 0 | 0 | 0 |
| Total | 433 | 86 | 3 | 24 | 8 | 120 |
*
According to our investigation records, the patient was infected in Egypt. However, Egypt had already eradicated malaria in the 1990s. The patient should have been infected in other African countries. But, the exact place of the infection can not be confirmed now, because we lost contact with the patient in 2013.