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. 2018 Apr 5;3(7):e93247. doi: 10.1172/jci.insight.93247

Figure 3. Network modeling of the overlap of gene expression between clinical markers.

Figure 3

(A) Network models generated using BioGRID (version 3.2.117) were analyzed to define modules of functionally related genes. The “community structure” of these modules was assessed and ranked by their “centrality” score to form a hierarchy related to the biological action of the network. (B) Community structure of modules within the network was assessed using the ModuLand algorithm in Cytoscape 2.8.3. Hierarchy of the first 15 network modules in each of the network models of gene expression overlap between clinical markers. Modules are shown as octagons labeled with the most central gene in the cluster and ranked by network centrality (1st through 15th).