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Schematic of MM-DX-929 - a liposomal PET imaging companion diagnostic agent. MM-DX-929 is a highly PEGylated (10 mol%) untargeted liposome, stably encapsulating 64Cu:4-DEAP-ATSC complex and excess uncomplexed 4-DEAP-ATSC chelators. PEG-DSPE = polyethylene glycol-1,2-distearoyl-sn-glycerol-3-phosphoethanolamine; TEA-SOS = triethylammonium sucrose octasulfate; DSPC = 1,2-distearoyl-sn-glycero-3-phosphocholine.
