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. 2018 Mar 28;8(9):2496–2507. doi: 10.7150/thno.24677

Figure 4.

Figure 4

Working model for DWORF (from LOC100507537) function. DWORF localizes to the SR membrane, where it enhances SERCA activity by displacing the SERCA inhibitor PLN. (DWORF: dwarf open reading frame). Adapted with permission from 54, copyright 2016 Springer.