OXT suppressed the invasion and migration of human ovarian cancer cell line A2780. (A) A2780 cells were seeded in the upper chamber treated with 0, 10-9, 10-8, 10-7 and 10-6 M of OXT and allowed to migrate for 24 hours; then, the migrated cells were stained with crystal violet. OXT dose-dependently depressed the invasion of human ovarian cancer cell line A2780. The graphs depict the mean ± SD of three independent experiments. *, P < 0.05. (B) The effect of oxytocin on A2780 cells cells migration ability was plotted as the percentage of wound closure. OXT reduced the scratch-induced wound healing in human ovarian cancer cell line A2780. The graphs depict the mean ± SD of three independent experiments. *, P < 0.05.