Table 5.
Genetic models | Genotypes | N(cases/controls) | Crude OR(95% CI) | Adjusted OR(95% CI)a | Pa |
---|---|---|---|---|---|
Additive | TT | 266/308 | 1.18 (1.03-1.35) | 1.19 (1.04-1.37) | 0.014 |
CT | 423/414 | ||||
CC | 159/133 | ||||
Co-dominant | TT | 266/308 | 1.00 | 1.00 | |
CT | 423/414 | 1.18(0.96-1.46) | 1.15(0.92-1.43) | 0.227 | |
CC | 159/133 | 1.38(1.04-1.84) | 1.45(1.09-1.94) | 0.012 | |
Dominant | TT | 266/308 | 1.00 | 1.00 | |
CT/CC | 582/547 | 1.23(1.01-1.51) | 1.22(0.99-1.50) | 0.062 | |
Recessive | TT/CT | 689/722 | 1.00 | 1.00 | |
CC | 159/133 | 1.25(0.97-1.61) | 1.34(1.03-1.73) | 0.027 |
a Logistic regression analysis with adjustment for age and smoking