Table 1.
Clinical characteristics of gastric cancer patients
|
Variable |
Patients N=197 (%) |
Deaths N=85 (%) |
MST (months) |
Log-rank P |
HR (95% CI) univariate |
P value |
HR (95% CI) multivariate |
P value2 |
|---|---|---|---|---|---|---|---|---|
| Age (years) | ||||||||
| ≤65 | 113 (57.4) | 41 (48.2) | 42.551 | 0.014 | 1.00 | 0.016 | 1.00 | 0.493 |
| >65 | 84 (42.6) | 44 (51.8) | 40.00 | 1.69 (1.11-2.59) | 1.21 (0.70-2.08) | |||
| Sex | ||||||||
| Male | 129 (65.5) | 57 (67.1) | 56.53 | 0.568 | 1.00 | 0.568 | 1.00 | 0.065 |
| Female | 68 (34.5) | 28 (32.9) | 35.001 | 0.88 (0.56-1.38) | 0.64 (0.39-1.03) | |||
| Drinking status | ||||||||
| No | 173 (87.8) | 77 (90.6) | 38.971 | 0.266 | 1.00 | 0.270 | 1.00 | 0.549 |
| Yes | 24 (12.2) | 8 (9.4) | 44.241 | 0.66 (0.32-1.38) | 0.79 (0.37-1.70) | |||
| Tumor size (cm) | ||||||||
| ≤ 4 | 113 (57.4) | 35 (41.2) | 42.881 | <0.001 | 1.00 | <0.001 | 1.00 | 0.029 |
| > 4 | 84 (42.6) | 50 (58.8) | 35.10 | 2.33 (1.51-3.59) | 1.70 (1.06-2.74) | |||
| Tumor site | ||||||||
| Cardia | 21 (10.7) | 11 (12.9) | 40.30 | 0.312 | 1.00 | 0.314 | 1.00 | 0.158 |
| Non-cardia | 176 (89.3) | 74 (87.1) | 40.341 | 0.72 (0.38-1.36) | 0.62 (0.32-1.20) | |||
| Tumor differentiation | ||||||||
| Well/Moderate | 47 (23.9) | 17 (20.0) | 42.231 | 0.200 | 1.00 | 0.203 | 1.00 | 0.427 |
| Poor | 150 (76.1) | 68 (80.0) | 56.53 | 1.41 (0.83-2.41) | 0.80 (0.45-1.40) | |||
| Depth of invasion | ||||||||
| T1/T2 | 66 (33.5) | 7 (8.2) | 50.871 | <0.001 | 1.00 | <0.001 | 1.00 | 0.017 |
| T3/T4 | 131 (66.5) | 78 (91.8) | 33.27 | 7.71 (3.55-16.72) | 3.25 (1.23-8.58) | |||
| Lymph node metastasis | ||||||||
| N0 | 72 (36.5) | 15 (17.6) | 35.241 | <0.001 | 1.00 | <0.001 | 1.00 | 0.911 |
| N1/N2/N3 | 125 (63.5) | 70 (82.4) | 38.53 | 3.23 (1.85-5.64) | 0.94 (0.33-2.73) | |||
| Distant metastasis | ||||||||
| M0 | 193 (98.0) | 81 (95.3) | 40.311 | <0.001 | 1.00 | 0.001 | 1.00 | 0.271 |
| M1 | 4 (2.0) | 4 (4.7) | 11.30 | 5.26 (1.90-14.62) | 1.87 (0.61-5.68) | |||
| TNM stage | ||||||||
| I/II | 97 (49.2) | 20 (23.5) | 47.071 | <0.001 | 1.00 | <0.001 | 1.00 | <0.001 |
| III/IV | 100 (50.8) | 65 (76.5) | 23.55 | 4.27 (2.58-7.07) | 3.63 (2.08-6.34) | |||
| Vascular/Lymphatic vessel/Perineural invasion | ||||||||
| No | 152 (77.2) | 53 (62.4) | 43.691 | <0.001 | 1.00 | <0.001 | 1.00 | <0.001 |
| Yes | 45 (22.8) | 32 (37.6) | 18.17 | 3.05 (1.95-4.76) | 2.44 (1.51-3.94) | |||
| Chemotherapy | ||||||||
| No | 95 (48.2) | 42 (49.4) | 51.27 | 0.408 | 1.00 | 0.408 | 1.00 | 0.036 |
| Yes | 102 (51.8) | 43 (50.6) | 41.201 | 0.84 (0.55-1.28) | 0.55 (0.31-0.96) | |||
Abbreviations: MST, median survival time; HR, hazard ratio; CI, confidence interval.
1 Mean survival time was provided when MST could not be calculated.
2 Adjusted for age, sex, drinking status, tumor size, tumor site, tumor differentiation, TNM stage, vascular/lymphatic vessel/perineural invasion, chemotherapy.