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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2016 Sep 9;26(11):1826–1835. doi: 10.1016/j.euroneuro.2016.08.014

Figure 6.

Figure 6

Effect of inactivation of MCHR1 on Milk production and pituitary prolactin mRNA in postpartum female WT and MCHR1 KO mice. (A) The milk production of WT and MCHR1 KO mice (n = 5–6) on PPD10 and PPD12. Two way ANOVA followed by Bonferroni post-hoc test (F1,18 = 285.4, P < 0.001): WT vs. KO, PPD10: ***P < 0.001, PPD11: ***P < 0.001. (B) The effect of GW803430 (30 mg/kg) on the milk production of WT mice on PPD11 (n = 5). Unpaired t-test (t = 6.3): vehicle vs. GW803430, ***P < 0.001. (C) The relative prolactin mRNA levels in the pituitary of WT and MCHR1 KO mice on PPD2 and PPD16 measured by qtPCR (n = 3). Unpaired t-test (PPD2: t = 3.2; PPD16: t = 5.1): WT vs. KO, **P < 0.01, ***P < 0.001.