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. 2018 Apr 24;9:876. doi: 10.3389/fimmu.2018.00876

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Copyright © 2018 Sieghart, Platzer, Studenic, Alasti, Grundhuber, Swiniarski, Horn, Haslacher, Blüml, Smolen and Steiner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Number of antibody positivities in rheumatoid arthritis (RA) patients and disease controls. 290 RA patients and 261 disease controls were tested for the presence of IgA, IgG, and IgM isotypes of rheumatoid factor, anti-citrullinated protein antibodies and RA33. The number of antibodies detected in a patient’s serum is indicated on the x-axis; the number of patients is indicated on the y-axis. Disease controls were found to have significantly (p < 0.001) fewer antibody positivities (1–2 Abs) compared to RA patients who commonly had more than two antibodies (3–8 Abs).