Skip to main content
. Author manuscript; available in PMC: 2019 Jan 5.
Published in final edited form as: Curr Opin Cell Biol. 2018 Jan 5;49:91–98. doi: 10.1016/j.ceb.2017.12.010

Figure 2. The mROS conundrum.

Figure 2

Schematic representation of the presumed roles of mROS in HSC function and in hypoxia signaling. mROS directly negatively affect HSC function, but may on the other hand stabilize HIF and activate glycolysis, which is required for maintaining HSC function.