Table 2.
Risk factors for tuberculosis infection among household contacts of tuberculosis cases
| Variable | No. of household contacts | No. tuberculosis infection (%) | Univariable model (N = 1,064) | |
|---|---|---|---|---|
| cOR (95% CI) | P value | |||
| N | 1,064 | 276 (25.9) | – | – |
| Age | 0.967 | |||
| < 15 | 191 | 50 (26.2) | Reference | – |
| 15–42 | 334 | 88 (26.3) | 1.01 (0.67–1.51) | 0.966 |
| ≥ 42 | 539 | 138 (25.6) | 0.97 (0.67–1.41) | 0.876 |
| Sex | ||||
| Male | 446 | 116 (26.0) | Reference | – |
| Female | 618 | 160 (25.9) | 0.99 (0.75–1.31) | 0.965 |
| Drug resistance profile of index case | ||||
| Drug-susceptible | 667 | 165 (24.7) | Reference | – |
| Multidrug-resistant | 397 | 111 (28.0) | 1.18 (0.89–1.56) | 0.246 |
| Region of Jiangsu Province | < 0.001 | |||
| South | 243 | 23 (9.5) | Reference | – |
| Middle | 217 | 91 (41.9) | 6.91 (4.16–11.47) | < 0.001 |
| North | 604 | 162 (26.8) | 3.51 (2.20–5.59) | < 0.001 |
| Previous tuberculosis Exposure | ||||
| No | 691 | 125 (18.1) | Reference | – |
| Yes | 373 | 151 (40.5) | 3.08 (2.32–4.09) | < 0.001 |
| BCG vaccinated | ||||
| Yes | 763 | 206 (27.0) | Reference | – |
| No | 301 | 70 (23.3) | 0.82 (0.60–1.12) | 0.210 |
| No. family members | ||||
| ≤ 4 | 762 | 181 (23.8) | Reference | – |
| > 4 | 302 | 95 (31.5) | 1.47 (1.10–1.98) | 0.010 |
| Independent kitchen | ||||
| No | 109 | 39 (35.8) | Reference | – |
| Yes | 955 | 237 (24.8) | 0.59 (0.39–0.90) | 0.014 |
| No. bedrooms | ||||
| ≤ 4 | 824 | 204 (24.8) | Reference | – |
| > 4 | 239 | 72 (30.1) | 1.31 (0.95–1.80) | 0.096 |
| Smoking | ||||
| Yes | 211 | 58 (27.5) | Reference | – |
| No | 853 | 218 (25.6) | 0.91 (0.65–1.27) | 0.567 |
BCG = Bacille Calmette-Guérin; cOR = crude odds ratio.