Table 1.
Bivariable and multivariable analyses for IS6110 restrict fragment length polymorphism (RFLP) clustering among indigenous patients with TB
| RFLP clustered | Unique profile | ||||
|---|---|---|---|---|---|
| Variables | (number/percentage) | P value | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Sex, male | 23/38 (60) | 15/22 (68) | 0.553 | – | – |
| Domestic overcrowding* | 29/35 (83) | 11/21 (52) | 0.008 | 4.83 (1.44–16.26) | 6.10 (1.50–24.88)§ |
| BCG vaccine scar | 24/36 (67) | 19/22 (86) | 0.096 | 0.32 (0.08–1.28) | – |
| Alcohol use | 9/38 (24) | 7/22 (32) | 0.492 | – | – |
| Smoking | 6/38 (16) | 1/21 (5) | 0.210 | – | – |
| Illicit drug use over the last year | 3/38 (8) | 1/22 (5) | 0.616 | – | – |
| History of contact with TB case | 31/38 (82) | 10/21 (48) | 0.007 | 4.87 (1.49–15.95) | – |
| Household contact | 8/38 (21) | 0/22 (0) | 0.021 | † | – |
| HIV/AIDS | 1/34 (3) | 0/20 (0) | 0.439 | † | – |
| Previous TB | 4/37 (11) | 5/22 (23) | 0.218 | – | – |
| Homeowner | 30/38 (79) | 21/22 (95) | 0.084 | 5.60 (0.65–48.19) | – |
| Individual income < US$100 | 23/35 (66) | 11/21 (52) | 0.323 | – | – |
| Social class ≤ 10 from the median (D or E)‡ | 31/38 (82) | 11/21 (52) | 0.018 | 3.69 (1.14–11.93) | 3.72 (1.00–13.98)§ |
| Less than 4 year of schooling | 23/38 (60) | 9/21 (43) | 0.192 | – | – |
| Living with partner | 23/38 (60) | 12/22 (54) | 0.651 | – | – |
| Sugarcane worker | 4/38 (10) | 8/22 (36) | 0.016 | 0.21 (0.05–0.80) | – |
AIDS = acquired immune deficiency syndrome; BCG = Bacillus Calmette–Guérin; CI = confidence interval; HIV = human immunodeficiency virus; OR = odds ratio; TB = tuberculosis.
*
More than two individuals per room.
†
The logit estimators use a correction of 0.5 in every cell of those tables that contain a zero.
‡
Social class was categorized according to the classifications set forth by the Brazilian Association of Research Institutes and grouped according to the number of 10-point intervals (class D or E) that fell below the median.
§
Variables with P < 0.05.