Table 2.
Maternal Trypanosoma cruzi serology at delivery and polymerase chain reaction (PCR) and genotyping in maternal blood from seropositive mothers (with at least one positive antibody rapid test in cord blood and a positive enzyme-linked immunosorbent assay [ELISA] Wiener in maternal blood) by country
Argentina (N = 9,390) | Honduras (N = 6,595) | Mexico (N = 12,160) | ||||
---|---|---|---|---|---|---|
n/N | % | n/N | % | n/N | % | |
Rapid tests in cord blood | ||||||
Both rapid tests positive | 129/9,339 | 1.4 | 183/6,583 | 2.8 | 38/12,067 | 0.3 |
Only Stat-Pak positive | 22/9,339 | 0.2 | 39/6,583 | 0.6 | 36/12,067 | 0.3 |
Only T-Detect positive | 4/9,339 | 0.1 | 9/6,583 | 0.1 | 35/12,067 | 0.3 |
ELISA Wiener in maternal blood* † | ||||||
Positive | 134/154 | 87.0 | 181/230 | 78.7 | 32/109 | 29.4 |
Negative | 20/154 | 13.0 | 49/230 | 21.3 | 75/109 | 68.8 |
Inconclusive | 0/154 | 0.0 | 0/230 | 0.0 | 2/109 | 1.8 |
PCR in maternal blood‡ § | ||||||
Positive | 105/134 | 78.4 | 132/181 | 72.9 | 17/32 | 53.1 |
Negative | 29/134 | 21.6 | 49/181 | 27.1 | 15/32 | 46.9 |
Genotyping in maternal blood‡ ‖ | ||||||
Only non-TcI | 23/105 | 21.9 | 54/132 | 40.9 | 6/17 | 35.3 |
Only TcI | 6/105 | 5.7 | 1/132 | 0.8 | 1/17 | 5.9 |
Both TcI and non-TcI | 6/105 | 5.7 | 10/132 | 7.6 | 0/17 | 0.0 |
Undetermined | 70/105 | 66.7 | 67/132 | 50.8 | 10/17 | 58.8 |
Among women with at least one positive rapid test in cord blood.
P < 0.01.
Among women with at least one positive rapid test in cord blood and a positive ELISA Wiener in maternal blood.
P = 0.015.
P = 0.009.