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. 2018 Apr 13;9(28):19508–19524. doi: 10.18632/oncotarget.24628

Figure 5.

Figure 5

(A) KLγ was expressed in urothelial carcinomas of the bladder and the expression level gradually increased as tumors progressed to higher stages and grades. Scale bars, 100 μm. (B) Quantification of KLγ expression level in non-muscle invasive bladder cancer (NMIBC) versus muscle invasive bladder cancer (MIBC). The expression level of KLγ was significantly higher in MIBC than NMIBC. (C) Although patients with the high KLγ expression were tended to have the intravesical recurrence in non-muscle invasive bladder cancer, there was no significant difference. (D) Patients with the high KLγ expression significantly progressed to muscle invasive bladder cancer compared to patients with the low KLγ expression in non-muscle invasive bladder cancer. (E) Although patients with the high KLγ expression were tended to have the recurrence in muscle invasive bladder, there was no significant difference. (F) There was no significant difference of disease-specific survival between patients with low KLγ expression and those with high KLγ expression in muscle invasive bladder cancer. (G) There was no significant difference of overall survival between patients with low KLγ expression and those with high KLγ expression in muscle invasive bladder cancer.