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. 2018 Apr 13;9(28):19555–19568. doi: 10.18632/oncotarget.24656

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Copyright: © 2018 Dobashi et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) The numbers of cases with mutations stratified based on prognostic group in the discovery cohort are presented. Numbers above each bar represent P-values for Fisher’s exact test. All detected mutations before manual inspection are listed. (B) Genes that showed different mutations between the positive and poor prognostic groups are shown in each case of the cohort. Statistical power was calculated based on the method reported by Lawrence et al. [44] (C) The CIRCOS plot of copy number variation in the discovery cohort. The figure on the right is an enlarged view of 17p. Six of eight (75%) TP53 mutations and six of 11 (55%) 17p deletions were found to coexist in the discovery cohort.