Table 2. OSBPL10 was identified as a SHM target.
Gene | Total SNVs | Motif mutation | Transition mutation | C:G mutation | SHM indicator |
---|---|---|---|---|---|
PIM1* | 588 | 426 | 406 | 583 | < 0.001 |
IGLL5 | 482 | 359 | 254 | 429 | < 0.001 |
PABPC3 | 386 | 69 | 276 | 151 | < 0.001 |
KCNJ18 | 214 | 0 | 102 | 214 | < 0.001 |
CTBP2 | 209 | 31 | 93 | 111 | 0.0025 |
ZNF717 | 161 | 14 | 89 | 135 | 0.0018 |
MUC3A | 161 | 25 | 75 | 76 | 0.0068 |
ATAD3B | 120 | 0 | 120 | 120 | < 0.001 |
MUC6 | 110 | 20 | 23 | 98 | < 0.001 |
LDHAL6B | 108 | 27 | 84 | 30 | 0.0073 |
MTCH2 | 107 | 3 | 81 | 32 | < 0.001 |
CD79B | 90 | 4 | 63 | 7 | < 0.001 |
PABPC1 | 88 | 6 | 39 | 24 | < 0.001 |
CDC27 | 76 | 30 | 66 | 0 | < 0.001 |
HLA-DRB1 | 74 | 37 | 32 | 35 | 0.0408 |
MYD88 | 72 | 4 | 68 | 8 | < 0.001 |
BTG1* | 71 | 53 | 54 | 67 | 0.0024 |
DUSP2* | 71 | 42 | 57 | 62 | 0.0273 |
ANKLE1 | 68 | 0 | 0 | 8 | < 0.001 |
AK2 | 63 | 52 | 32 | 61 | 0.0013 |
SHANK3 | 61 | 21 | 61 | 17 | 0.0176 |
AQP7 | 58 | 1 | 32 | 57 | 0.0060 |
CNN2 | 43 | 31 | 39 | 24 | 0.0232 |
MPEG1 | 40 | 28 | 31 | 40 | 0.0307 |
HNRNPL | 39 | 0 | 36 | 0 | < 0.001 |
OSBPL10 | 30 | 28 | 22 | 27 | 0.0175 |
KLRC2 | 29 | 25 | 4 | 25 | 0.0039 |
ARMC4 | 28 | 8 | 0 | 20 | 0.0109 |
FAM205A | 28 | 18 | 28 | 9 | 0.0387 |
*: previously reported gene.