Table 1. Number of hDEGs and DEGs and their regulation between oxygen conditions and model stages.

Between oxygen conditions (hDEGs)
Regulation	Primary BJ	Immortalized	Transformed	Metastasizing
Up	375	295	778	353
Down	534	795	469	441
Total	909	1090	1247	794
Within model (DEGs, atmospheric oxygen)
Regulation	Primary versus immortalized	Immortalized versus transformed	Transformed versus metastasizing
Up	1056	2275	562
Down	889	1536	404
Total	1945	3811	966