Table 2. Characteristics of individual patients.
| Case | Age | Sex | Family history of cancer | Disease status | Oxaliplatin-based regimen | Identification of HRR-related gene mutations |
|---|---|---|---|---|---|---|
| 1 | 66 | F | Unknown | Metastatic | FOLFIRINOX | No |
| 2 | 52 | F | Gastric cancer (FDR), Colorectal cancer (TDR), Lung cancer (TDR) | Metastatic | FOLFIRINOX | No |
| 3 | 42 | M | Pancreatic cancer (SDR) | Locally advanced | SOX | No |
| 4 | 64 | M | None | Locally advanced | GEMOX | No |
| 5 | 39 | F | Cutaneous cancer (FDR) Esophageal cancer (TRD) |
Metastatic | SOX | No |
| 6 | 64 | M | None | Recurrence after adjuvant S-1 | SOX | No |
| 7 | 74 | F | Lung cancer (FDR) | Recurrence after adjuvant S-1 | SOX | No |
| 8 | 65 | M | Gastric cancer (FDR), Lung cancer (TDR) | Metastatic | SOX | No |
| 9 | 66 | F | Unknown | Recurrence after adjuvant S-1 | GEMOX | No |
| 10 | 55 | M | None | Metastatic | FOLFIRINOX | Yes |
| 11 | 52 | M | Brain tumor (FDR) Prostate cancer (TRD) |
Locally advanced | FOLFIRINOX | Yes |
| 12 | 68 | M | Gastric cancer (FDR) | Metastatic | FOLFIRINOX | Yes |
| 13 | 47 | M | Pancreatic cancer (FDR) | Metastatic | GEMOX | Yes |
| 14 | 44 | M | None | Recurrence after adjuvant S-1 | SOX | Yes |
| 15 | 65 | F | Gastric cancer, Colorectal cancer (FDR) | Metastatic | FOLFOX | Yes |
| 16 | 81 | M | Unknown cancer (FDR) | Metastatic | SOX | Yes |
| 17 | 57 | F | Gastric cancer (FDR) | Recurrence | SOX | Yes |
| 18 | 65 | M | Biliary tract cancer (FDR) | Recurrence | - | No |
| 19 | 45 | M | None | Metastatic | - | No |
| 20 | 73 | M | Colorectal cancer (FDR) | Recurrence after adjuvant S-1 | - | No |
| 21 | 60 | F | Pancreatic cancer (FDR) | Recurrence after adjuvant S-1 | - | No |
| 22 | 59 | F | Gastric cancer (SDR) Pancreatic cancer (TDR) |
Recurrence after adjuvant S-1 | - | No |
| 23 | 67 | M | None | Recurrence | - | No |
| 24 | 60 | F | Unknown | Recurrence after adjuvant S-1 | - | Yes |
| 25 | 61 | M | Breast cancer (FDR) | Locally advanced | - | Yes |
| 26 | 67 | F | Gastric cancer (FDR) | Locally advanced | - | Yes |
| 27 | 77 | F | Unknown | Locally advanced | - | Yes |
| 28 | 74 | F | None | Locally advanced | - | Yes |
FDR, first-degree relative; SDR, second-degree relative; TDR, third-degree relative.