Table 2. Ceramide levels of tissue samples and of the subgroups tumor, size and LN status are shown.
Number of patients | Ctotal | p value | C14:0 | p value | C16:0 | p value | C18:1 | p value | C18:0 | P value | |
---|---|---|---|---|---|---|---|---|---|---|---|
Tumor size | |||||||||||
≤ 2cm | 18 | 3.799 | 0.030 | 0.051 | 0.034 | 1.152 | 0.197 | 0.086 | 0.377 | 0.140 | 0.159 |
>2cm | 26 | 7.327 | 0.080 | 1.375 | 0.097 | 0.199 | |||||
LN status | |||||||||||
Negative | 40 | 5.073 | 0.541 | 0.069 | 0.441 | 1.344 | 0.373 | 0.095 | 0.292 | 0.152 | 0.338 |
Positive | 4 | 3.545 | 0.048 | 0.865 | 0.058 | 0.172 | |||||
ER status | |||||||||||
Negative | 10 | 3.229 | 0.026 | 0.047 | 0.168 | 0.821 | 0.041 | 0.060 | 0.238 | 0.112 | 0.339 |
Positive | 34 | 5.871 | 0.075 | 1.592 | 0.098 | 0.155 | |||||
PgR status | |||||||||||
Negative | 16 | 3.602 | 0.015 | 0.042 | 0.017 | 1.035 | 0.081 | 0.064 | 0.366 | 0.169 | 0.577 |
Positive | 28 | 5.982 | 0.087 | 1.679 | 0.096 | 0.152 | |||||
HER2 status | |||||||||||
Negative | 29 | 6.158 | 0.055 | 0.086 | 0.028 | 1.557 | 0.271 | 0.134 | 0.340 | 0.152 | 0.393 |
Positive | 15 | 3.602 | 0.053 | 1.079 | 0.071 | 0.119 |
C20:0 | p value | C22:0 | p value | C24:1 | p value | C24:0 | p value | C26:1 | p value | C26:0 | p value | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumor size | ||||||||||||
<2cm | 0.158 | 0.073 | 0.437 | 0.025 | 0.924 | 0.045 | 0.651 | 0.012 | 0.485 | 0.009 | 0.008 | 0.016 |
≥ 2cm | 0.213 | 1.036 | 2.386 | 1.400 | 0.119 | 0.021 | ||||||
LN status | ||||||||||||
Negative | 0.206 | 0.207 | 0.579 | 0.395 | 1.248 | 0.373 | 0.840 | 0.829 | 0.079 | 0.595 | 0.011 | 0.239 |
Positive | 0.137 | 0.417 | 0.877 | 0.774 | 0.095 | 0.026 | ||||||
ER status | ||||||||||||
Negative | 0.117 | 0.047 | 0.221 | 0.019 | 0.847 | 0.051 | 0.402 | 0.044 | 0.048 | 0.168 | 0.007 | 0.186 |
Positive | 0.207 | 0.798 | 1.435 | 0.885 | 0.092 | 0.013 | ||||||
PgR status | ||||||||||||
Negative | 0.123 | 0.028 | 0.264 | 0.011 | 0.902 | 0.014 | 0.356 | 0.095 | 0.049 | 0.085 | 0.007 | 0.015 |
Positive | 0.219 | 0.845 | 1.820 | 0.973 | 0.097 | 0.014 | ||||||
HER2 status | ||||||||||||
Negative | 0.208 | 0.177 | 0.782 | 0.116 | 1.522 | 0.155 | 0.097 | 0.105 | 0.097 | 0.055 | 0.012 | 0.379 |
Positive | 0.151 | 0.510 | 0.911 | 0.563 | 0.048 | 0.011 |
HER2, human epidermal growth factor receptor 2.