Table 1. Characteristics of patients with or without END.
| Patients with END (n = 95) | Patients without END (n = 280) | p value | |
|---|---|---|---|
| Age (years) | 70.2 ± 11.4 | 67.8 ± 13.6 | 0.017 |
| Male (n, %) | 59 (62.1) | 183 (65.4) | 0.562 |
| Hypertension (n, %) | 76 (80.0) | 217 (77.5) | 0.633 |
| Diabetes mellitus (n, %) | 51 (53.7) | 106 (37.9) | 0.008 |
| Current smoker (n, %) | 40 (42.1) | 118 (42.1) | 0.997 |
| Body mass index (kg/m2) | 24.1 ± 5.8 | 23.9 ± 6.3 | 0.883 |
| Previous MI (n, %) | 5 (5.3) | 13 (4.6) | 0.834 |
| Hyperlipidemia (n, %) | 67 (70.5) | 195 (69.6) | 0.931 |
| Fasting blood glucose (mmol/L) | 7.8 ± 2.5 | 6.5 ± 2.6 | <0.001 |
| Hemoglobin A1c (%) | 7.5 ± 1.9 | 6.7 ± 2.1 | <0.001 |
| Admission NIHSS | 6.1 ±1.9 | 5.9 ± 1.8 | 0.344 |
| Stroke subtype | |||
| Atherothrombotic (n, %) | 59 (62.1) | 172 (61.4) | 0.987 |
| Small artery disease (n, %) | 36 (37.9) | 108 (38.6) | 0.987 |
| Previous treatment (n, %) | |||
| Antihypertensive drugs | 39 (41.1) | 124 (44.3) | 0.523 |
| Hypoglycemic drugs | 38 (40.0) | 102 (36.4) | 0.541 |
| Statins | 15 (15.8) | 49 (17.5) | 0.712 |
| Aspirin | 24 (25.3) | 81(28.9) | 0.492 |
| In-hospital treatment (n, %) | |||
| Antihypertensive drugs | 83 (87.4) | 239 (85.4) | 0.644 |
| Hypoglycemic drugs | 56 (58.9) | 140 (50.0) | 0.123 |
| Statins | 94 (98.9) | 275 (98.2) | 0.992 |
| Clopidogrel plus aspirin | 57 (60.0) | 174 (62.1) | 0.721 |
| Clopidogrel alone | 38 (40.0) | 106 (37.9) | 0.721 |
END, early neurological deterioration; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale.