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. Author manuscript; available in PMC: 2019 Feb 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2018 Feb 3;341:106–113. doi: 10.1016/j.taap.2018.01.014

Figure 4. Low-level sodium arsenite causes transient ER stress.

Figure 4

(A–D) Immunoblot analysis of changes in cleaved ATF6, XBP1s, phosphorylated EIF2S1 (p-EIF2S1), and total EIF2S1 protein levels following treatment with the indicated time points and concentrations of sodium arsenite in NIH 3T3 (A), HeLa (B), HEK 293 (C), or HEMn-LP (D) cells. Starvation (HBSS), or 0.1 µM BAF for 2 or 4 h were used as controls. GAPDH was used as an internal loading control.