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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Free Radic Biol Med. 2016 Feb 27;95:96–111. doi: 10.1016/j.freeradbiomed.2016.02.029

Table 1.

Right ventricle and systemic hemodynamic parameters. RVPSP=right ventricle peak systolic pressure, RVPDP=right ventricle peak diastolic pressure, +dP/dt=maximum dP/dt, −dP/dt=minimum dP/dt, HR=heart rate, mean BP=mean blood pressure. Results are expressed as mean ± SEM: N=8 in each group.

Treatment RVPSP (mmHg) RVPDP (mmHg) +dP/dt (mmHg/s) −dP/dt (mmHg/s) HR (B/s) Mean-BP (mmHg)
Control 28.12±2.12 −3.71 ± 0.64 2604±192 −2604 ± 856 365±24 104±8
MCT 44.73±7.49a −1.91 ± 1.35a 3741±1461a −3384 ± 946 365±12 100 ±13
MCT+Gefitinib 30.42±4.45b −4.11 ± 1.67b 2557±384 −2623 ± 288 354±28 97±10
a1F-ANOVA, P< 0.00006 0.0049 0.047 0.118 0.97 0.42
b1F-ANOVA, P< 0.0013 0.019 0.06 0.064 0.38 0.69
a

P<0.05 vs. Control group.

b

P<0.05 vs. MCT group.