Table 1.

Spearman rank correlation between disease severity scores and baseline biomarker levels in patients with necrotizing soft tissue infection

	LRINEC		SAPS II		SOFA score*		Creatinine**
	Rho	P	Rho	P	Rho	P	Rho	P
Nitrite	−0.11	0.25	−0.13	0.15	−0.30	0.001	−0.23	0.009
l-Arginine	−0.13	0.17	0.09	0.33	0.02	0.87	−0.12	0.17
ADMA	−0.05	0.59	0.32	0.0002	0.22	0.01	0.17	0.048
l-Arginine/ADMA ratio	−0.07	0.43	−0.14	0.10	−0.12	0.18	−0.22	0.01

^*SOFA score day 1.

^**Highest value measured during the first 24 h of admission.

ADMA indicates asymmetric dimethylarginine; LRINEC, Laboratory Risk Indicator For Necrotizing Fasciitis; SAPS II, Simplified Acute Physiology Score II; SOFA, Sepsis-Related Organ Failure Assessment.