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. 2018 May 1;13(5):e0195699. doi: 10.1371/journal.pone.0195699

Table 2. The optimal threshold of quantitative parameters to diagnose the grading of ccRCC.

Group AUC Threshold Sensitivity Specificity
CP
70keV 0.857 109.24 87.1(30) 87.5 (24)
NIC 0.771 0.35 83.9 (29) 75.0 (20)
Slope 0.885 4.03 90.3 (32) 87.5(24)
PP
70keV 0.675 107.98 45.2 (16) 93.7 (25)
NIC 0.710 0.85 58.1 (20) 87.5 (24)
slope 0.693 3.65 58.1 (20) 87.5 (24)

NIC, normalized iodine concentration; CP, cortex phase; PP, parenchyma phase. Threshold 70keV are cited in Hounsfield (HU). Threshold NIC in CP and PP are represented as mg/mL. Sensitivity values are demonstrated as %. Data in parentheses are numbers of low-grade ccRCC lesions (n = 35) used to calculate percentages. Specificity values are cited as %. Data in parentheses are numbers of low-grade ccRCC lesions (n = 27) used to calculate percentages.