Table 2. Effect of Magumsan HS on in vitro secretion of TARC, IP-10, RANTES and Eotaxin of human keratinocyte cells as measured by enzyme-linked immunosorbent assay.
| Variable | Tx Group | Concentration (pg/ml) | Ratio | p-value | |
|---|---|---|---|---|---|
| HS/Control | HS+poly/poly | ||||
| TARC | Control | 3.09±0.98 | 0.99 | <0.001 | |
| HS | 3.05±1.46 | ||||
| Poly (I:C) | 353.0±117.2 | 0.18 | |||
| HS+poly (I:C) | 64.04±19.85 | ||||
| IP-10 | Control | 3.63±1.27 | 0.65 | <0.001 | |
| HS | 2.33±1.32 | ||||
| Poly (I:C) | 1,628±177.4 | 0.84 | |||
| HS+poly (I:C) | 1,374±200.6 | ||||
| RANTES | Control | 41.67±17.02 | 0.05 | 0.064 | |
| HS | 1.90±0.96 | ||||
| Poly (I:C) | 109,896±63,129 | 0.04 | |||
| HS+poly (I:C) | 4,009±1,093 | ||||
| Eotaxin | Control | 4.26±0.93 | 1.08 | 0.99 | |
| HS | 4.61±0.80 | ||||
| Poly (I:C) | 4.87±0.83 | 0.98 | |||
| HS+poly (I:C) | 4.75±0.84 | ||||
Values are presented as mean±standard deviation. HS: hot spring, TARC: thymus and activation-regulated chemokine, IP-10: interferon-γ induced protein-10, RANTES: normal T cell expressed and secreted, Tx: treatment, poly: TLR 3 agonist poly (I:C).