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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Kidney Int. 2017 Mar 6;92(1):201–213. doi: 10.1016/j.kint.2016.12.024

Figure 5.

Figure 5

Unsupervised principal component analysis (PCA) plot evaluating the development dnDSA, post-transplant d-sp T-cell alloreactivity in relation to kidney allograft function (serum creatinine) at 24 months. The unsupervised principal component analysis (PCA) segregated the patients into 2 different groups, those without d-sp T-cell alloreactivity (negative d-sp IFN-γ ELISPOT), absence of dnDSA and better preserved 24-month kidney allograft function from those transplant patients with high d-sp alloreactivity (positive d-sp IFN-γ ELISPOT), presence of de novo humoral immunity and worse 24-month allograft function. Percentages of variance were: 48.3% for principal component 1, 33% for principal component 2 and 10.9% for principal component 3 (PCA mapping= 92.2%).