Table 4.

Cox and Competing Risks Regression Models of All-Cause and Selected Common Causes of Death

	Hazard ratio (95%CI)	Adjusted hazard ratio (95% CI)
	All causes	Drug-related	Cardiovascular	Cancer	Liver-related	All others
Age	1.05 (1.04, 1.06)	0.99 (0.97, 1.01)	1.07 (1.05, 1.10)	1.07 (1.05, 1.10)	1.08 (1.05, 1.11)	1.04 (1.03, 1.06)
Female	0.87 (0.71, 1.07)	0.53 (0.33, 0.85)	0.84 (0.52, 1.38)	1.00 (0.62, 1.63)	1.24 (0.65, 2.35)	1.05 (0.74, 1.50)
White Race/ethnicity	0.92 (0.75, 1.14)	1.26 (0.72, 2.23)	0.77 (0.47, 1.28)	0.79 (0.49, 1.29)	1.47 (0.76, 2.86)	0.87 (0.61, 1.24)
HCV infection	1.99 (1.62, 2.46)	1.08 (0.62, 1.91)	0.87 (0.51, 1.46)	2.55 (1.52, 4.26)	1.92 (1.03, 3.60)	2.93 (2.06, 4.17)
Chronic pain	0.85 (0.70, 1.03)	0.77 (0.50, 1.18)	1.37 (0.82, 2.29)	0.77 (0.47, 1.26)	0.66 (0.38, 1.14)	1.01 (0.72, 1.42)
Tobacco use disorder	1.00 (0.80, 1.26)	1.21 (0.74, 1.98)	2.58 (1.60, 4.17)	0.98 (0.56, 1.70)	0.46 (0.20, 1.06)	0.67 (0.44, 1.02)
Alcohol use disorder	1.27 (1.05, 1.55)	1.22 (0.78, 1.92)	0.88 (0.54, 1.43)	0.73 (0.44, 1.22)	5.44 (2.95, 10.05)	1.21 (0.87, 1.69)
Cannabis use disorde	1.20 (0.93, 1.55)	0.72 (0.36, 1.45)	0.77 (0.36, 1.65)	0.78 (0.39, 1.55)	1.04 (0.50, 2.14)	1.74 (1.19, 2.54)