Table 1.
Subjects’ characteristics, respiratory chamber, and magnetic resonance imaging data.
| Non-Diabetics Patients | Type 2 Diabetics Patients | |
|---|---|---|
| Gender (Male/Female) | 31/31 | 23/21 |
| Race (%White/Black/Other) | 47/50/3 | 84/16/0 |
| Age (years) | 32.7 ± 10.80 | 57.7 ± 7.9* |
| Weight (kg) | 97.8 ± 31.8 | 95.9 ± 23.4 |
| Height (cm) | 171.4 ± 9.9 | 170.2 ± 10.0 |
| BMI (kg/m2) | 33.6 ± 11.8 | 32.7 ± 7.2 |
| Fat mass (kg) | 31.6 ± 22.7 | 33.0 ± 14.7 |
| Fat-free mass (kg) | 59.3 ± 11.0 | 61.8 ± 11.8 |
| Percent body fat (%) | 32.2 ± 15.6 | 34.0 ± 9.2 |
| Free fatty acids (mmol/L) | 0.421 ± 0.241 | 0.578 ± 0.142* |
| Triglycerides (mg/dL) | 93.0 ± 51.4 | 179.0 ± 123.0* |
| Total Cholesterol (mg/dL) | 184.0 ± 29.4 | 170.2 ± 10.0 |
| Glucose (mg/dL) | 94.0 ± 8.3 | 116.6 ± 22.2* |
| Insulin (mU/L) | 11.8 ± 10.7 | 19.4 ± 18.3* |
| HOMA-IR | 2.8 ± 2.6 | 5.9 ± 6.4* |
| 24 hour RQ | 0.889 ± 0.045 | 0.865 ± 0.032 |
| Sleep RQ | 0.874 ± 0.055 | 0.850 ± 0.038 |
| Fat oxidation (g/24hr/kgFFM) | 0.95 ± 0.87 | 1.29 ± 0.48 |
| Carbohydrate oxidation (g/24hr/kgFFM) | 5.15 ± 1.51 | 4.41 ± 1.11 |
| Soleus IMCL (% of oil signal) | 0.46 ± 0.25 | 0.71 ± 0.60 |
| Anterior Tibialis IMCL (% of oil signal) | 0.38 ± 0.20 | 0.79 ± 1.01 |
| Intrahepatic lipids (% of oil signal) | 0.02 ± 0.03 | 0.09 ± 0.12 |
Absolute unadjusted values are shown in the table. For statistical analyses, all estimates were adjusted for sex, age, and BMI and presented as mean ± SD. G=grams, hr=hour. kgFFM= kilograms of fat-free mass. IMCL = intramyocellular lipids. Data presented as mean ± standard deviation.
*
p<0.05