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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Brain Stimul. 2018 Jan 31;11(3):607–617. doi: 10.1016/j.brs.2018.01.028

Figure 4.

Figure 4

During rest, GPi-DBS only modulates motor cortical PAC in high β frequencies without causing a significant power change (A) Group average PSDs are plotted for S1 (left) and M1/PM (right), in the DBS-OFF condition, during rest at DBS-OFF (black trace) and DBS-ON (blue trace). Gray shade represents statistically significant difference observed by two-group test of spectrum. No significant difference was found after correction for multiple comparisons. (B) Average band power values during resting conditon (DBS-OFF (black), DBS-ON (blue)) are also compared. Asterisk (*) sign indicates statistically significant difference (P<0.05, tested by non-parametric Wilcoxon signed-rank test, corrected for multiple comparisons using Bonferroni). Each bar shows the mean (across the cohort) and 95% confidence interval of the mean. (C) On the left hand side, average z-score maps for the cohort are represented, during resting condition for DBS-OFF (top row) and DBS-ON (bottom row). On the right hand side, average preferred phase of coupling for low β-broadband γ (red) and high β-broad band γ (blue) are represented. (D) Comparing average PAC between DBS-OFF and DBS-ON indicates statistically significant suppression of high β-broadband γ PAC at M1/PM. Asterisk (*) indicates statistical significance at P<0.05 (Wilcoxon signed rank test, Bonferroni correction). Each bar shows the mean (across the cohort) and 95% confidence interval of the mean.