Figure 6.
Resting state cortical PAC is restored after termination of high frequency GPi-DBS (A) Average zscore maps for subgroup (N=8) of subjects with resting state recordings during DBS-OFF before high frequency stimulation (DBS-OFF-pre), high frequency stimulation (DBS-ON) and DBS-OFF after the high frequency stimulation (DBS-OFF-post), indicating the reversal of untreated state PAC in the sensorimotor cortex. Bottom row shows the average preferred phase of coupling for low β-broadband γ (red) and high β-broad band γ (blue). (B) Comparing average PAC between DBS-OFF-pre and DBS-OFF-post conditions indicated no statistically significant difference in the coupling strength between the conditions (P>0.1, Wilcoxon signed-rank test).