Cohort#1 |
N = 6, 2 months age, Wdr13+/0 and Wdr13-/0 Social isolation, Sucrose preference, Open field Test (OFT), Forced swim test (FST). OFT and FST were conducted before subjection to social isolation and after social isolation. There was a week of group housing between the OFT and FST and beginning of social isolation |
Cohort#2 |
N = 6, 2 months age, Wdr13+/0 and Wdr13-/0 non-stressed controls, OFT, FST |
Cohort#3 |
N = 6, 2 months age, Wdr13+/0 and Wdr13-/0 social isolation, OFT and FST conducted after social isolation |
Cohort#4 |
N = 10, 2 months age, Wdr13+/0 and Wdr13-/0 non-stressed controls, Sucrose preference, Elevated plus maze |
Cohort#5 |
N = 6, 2 months age, Wdr13+/0 and Wdr13-/0 social isolation, Elevated plus maze, and FST conducted after social isolation |
Cohort#6 |
N = 8, 4 months age, Wdr13+/0 and Wdr13-/0 social isolation, FST conducted after social isolation |
Cohort#7 |
N = 6, 7 months age, Wdr13+/0 and Wdr13-/0 social isolation, FST after social isolation |
Cohort#8 |
N = 7, 2 months age, Wdr13+/0 and Wdr13-/0 non-stressed control for imipramine experiment, FST |
Cohort#9 |
N = 7, 2 months age, Wdr13+/0 and Wdr13-/0 social isolation group for imipramine experiment-sham treatment, FST after social isolation |
Cohort#10 |
N = 7, 2 months age, Wdr13+/0 and Wdr13-/0 social isolation group for imipramine experiment – Imipramine treatment, FST after social isolation and imipramine treatment |