Table 1.
Pre-conception | Gestation | Post-gestation | |||||
---|---|---|---|---|---|---|---|
HAD | BAD | HAD | BAD | HAD | BAD | ||
Body weight (g) | 260.8 ± 2.2 | 249.5 ± 4.3* | 316.0 ± 3.6 | 303.1 ± 6.2 | 272.5 ± 6.2 | 267.3 ± 4.1 | |
Mean alcohol consumption (g/kg) | 1 h | 0.77 ± 0.1 | 3.4 ± 0.1◦◦◦ | 2.5 ± 0.2 | 2.4 ± 0.2 | 3.5 ± 0.5 | 3.5 ± 0.4 |
24 h | 3.5 ± 0.1 | 8.1 ± 0.3◦◦◦ | 3.4 ± 0.4 | 5.4 ± 0.6* | 5.6 ± 0.6 | 8.5 ± 0.4** | |
Alcohol preference % | 1 h | 52.0 ± 0.3 | 65.3 ± 0.8◦◦◦ | 55.8 ± 1.8 | 65.0 ± 2.2** | 47.9 ± 3.8 | 55.0 ± 3.5 |
24 h | 38.8 ± 0.2 | 54.8 ± 1.1◦◦◦ | 40.1 ± 2.7 | 48.4 ± 2.4* | 40.8 ± 4.2 | 49.0 ± 2.3 |
Data refer to mean ± SEM of alcohol consumption and preference of female rats (n = 8) along the 18 weeks of HAD and BAD paradigms.
p < 0.05,
p < 0.01 Student's t-test;
p < 0.001 Mann–Whitney test.