TABLE 2 .
The effect of each of the EDF peptides studied on the endoribonucleolytic activities of the M. tuberculosis toxins MazF-mt1, MazF-mt3, and MazF-mt6a
|
M. tuberculosis toxin |
EcEDF (NNWNN) |
BsEDF (RGQQNE) |
PaEDF-1 (INEQTVVTK) |
PaEDF-2 (VEVSDDGSGGNTSLSQ) |
PaEDF-3 (APKLSDGAAAGYVTKA) |
|---|---|---|---|---|---|
| MazF-mt1 | − | − | − | − | − |
| MazF-mt3 | + | − | ± | ± | + |
| MazF-mt6 | + | − | ± | ± | + |
a
“+” indicates a significant increase in the endoribonucleolytic activity of the EDF. “±” indicates a moderate increase in the endoribonucleolytic activity of the EDF. “−” indicates no effect on the endoribonucleolytic activity of the EDF.