TABLE 2.
Antimicrobial drug susceptibilities tested for nontyphoidal Salmonella enterica subsp. enterica isolates from urine, fecal, and blood samples of humans in the United States in 2015a
| Antimicrobial drug class | Subclass | Combinatory formulation | Drug |
|---|---|---|---|
| Drugs for which variability in the log2(MIC) data from urine, fecal, and blood samples was sufficient to perform the statistical equivalence testing | |||
| Aminoglycosides | -Micins | No | Gentamicin |
| -Mycins | No | Streptomycin | |
| β-Lactams | Penicillins, including amino-, carboxy-, and ureido-, with β-lactamase inhibitors | Yes | Amoxicillin with clavulanic acid |
| Penicillins, including amino-, carboxy-, and ureido- | No | Ampicillin | |
| Cephems | No | Cefoxitin | |
| No | Ceftiofur | ||
| Macrolides | Azalides | No | Azithromycin |
| Phenicols | NA | No | Chloramphenicol |
| Quinolones | Fluoroquinolones | No | Ciprofloxacin |
| Quinolones | No | Nalidixic acid | |
| Sulfonamides | NA | No | Sulfisoxazole |
| Tetracyclines | Tetracyclines | No | Tetracycline |
| Drugs for which variability in the log2(MIC) data from urine, fecal, and blood samples was insufficient to perform the statistical equivalence testing | |||
| β-Lactams | Cephems | No | Ceftriaxone |
| Sulfonamides | NA | Yes | Sulfamethoxazole with trimethoprim |
| Drugs for which statistical equivalence testing could not be performed because of a low no. of each urine and blood samples (n < 10) tested with the antimicrobials | |||
| β-Lactams | Penicillins, including amino-, carboxy-, and ureido-, with β-lactamase inhibitors | Yes | Piperacillin with tazobactam constant |
| Carbapenems | No | Imipenem | |
| Cephems with β-lactamase inhibitors | Yes | Cefotaxime with clavulanic acid Ceftazidime with clavulanic acid | |
| Cephems | No | Cefepime | |
| No | Cefotaxime | ||
| No | Cefquinome | ||
| No | Ceftazidime | ||
| Monobactams | No | Aztreonam |
a
The data were collected by the U.S. National Antimicrobial Resistance Monitoring System.