TABLE 3.

Antimicrobial drug susceptibilities tested for Escherichia coli isolates from cattle fecal pads

Antimicrobial drug class	Subclass	Combinatory formulation	Drug
Drugs for which variability in the log2(MIC) data from the two sample processing approaches was sufficient to perform the statistical equivalence testing
Aminoglycosides	-Mycins	No	Tobramycin
β-Lactams	Penicillins, including amino-, carboxy-, and ureido-	No	Ampicillin
	Penicillins, including amino-, carboxy-, and ureido-, with β-lactamase inhibitors	Yes	Ampicillin with sulbactam, 2:1 ratio
	Cephems	No	Cefazolin
		No	Ceftiofur
Macrolides	Macrolides	No	Tilmicosin
	Triamilides	No	Tulathromycin
Phenicols	NA	No	Florfenicol
Tetracyclines	Tetracyclines	No	Chlortetracycline
		No	Minocycline
		No	Oxytetracycline
		No	Tetracycline
Drugs for which variability in the log2(MIC) data from the two sample processing approaches was insufficient to perform the statistical equivalence testing
Aminoglycosides	-Micins	No	Amikacin
		No	Gentamicin
	-Mycins	No	Neomycin
		No	Spectinomycin
β-Lactams	Penicillins, including amino-, carboxy-, and ureido-	No	Penicillin
		No	Piperacillin
	Penicillins, including amino-, carboxy-, and ureido-, with β-lactamase inhibitors	Yes	Piperacillin with tazobactam constant
		Yes	Ticarcillin with clavulanic acid
	Carbapenems	No	Doripenem
		No	Ertapenem
		No	Imipenem
		No	Meropenem
	Monobactams	No	Aztreonam
	Cephems	No	Cefepime
		No	Ceftazidime
		No	Ceftriaxone
Macrolides	Macrolides	No	Tylosin
Nitrofurans	NA	No	Nitrofurantoin
Pleuromutilins	NA	No	Pleuromutilin
		No	Tiamulin
Lincosamides	NA	No	Clindamycin
Quinolones	Quinolones	No	Nalidixic acid
	Fluoroquinolones	No	Ciprofloxacin
		No	Danofloxacin
		No	Enrofloxacin
		No	Levofloxacin
Sulfonamides	NA	No	Sulfadimethoxine
		Yes	Sulfamethoxazole with trimethoprim
Tetracyclines	Glycylcyclines	No	Tigecycline