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Tertiary-structure overlay of BT3130 (green) and BT3965 (orange) and (inset) a close-up view of the rear face of the molecule showing helices 1 and 2 that form the structural spine linking the N- and C-terminal domains. The left and right panels represent a 180° rotation around the vertical axis; The N-terminus, C-terminus and inter-domain space containing the catalytic active site are indicated.
