Table 1.
Baseline characteristics of cases with pancreatic cancer and control subjects1
| Factor | Controls (N=448) | Cases (N=448) | P-value2 | |
|---|---|---|---|---|
| Age at recruitment (years, mean ± SD) | 57.8 ± 7.8 | 57.8 ± 7.8 | matched | |
| Sex, n (%) | matched | |||
| Male | 213 | 213 | ||
| Female | 235 | 235 | ||
| Age at blood collection (±3 years) | 58.0 ± 7.8 | 58.0 ± 7.8 | matched | |
| Fasting status, n (%) | matched | |||
| Fasting (≥6 h) | 104 (23.2) | 112 (25.0) | ||
| In between (3–6 h) | 69 (15.4) | 68 (15.2) | ||
| Not-fasting (<3 h) | 172 (38.4) | 172 (38.4) | ||
| Unknown | 103(23.0) | 96 (21.4) | ||
| Height (cm, mean ± SD) | ||||
| Male | 175.1 ± 7.6 | 174.6 ± 7.3 | 0.68 | |
| Female | 161.4 ± 7.0 | 162.2 ± 6.5 | 0.19 | |
| Weight (kg, mean ± SD) | ||||
| Male | 82.1 ± 12.6 | 81.7 ± 11.7 | 0.69 | |
| Female | 65.6 ± 11.0 | 69.5 ± 13.3 | 0.0004 | |
| Waist to hip ratio (mean ± SD) | ||||
| Male | 0.95 ± 0.06 | 0.95 ± 0.06 | 0.62 | |
| Female | 0.81 ± 0.06 | 0.81 ± 0.07 | 0.15 | |
| Smoking status (%) | ||||
| Never | 194 (43.3) | 165 (36.8) | ||
| Former | 153 (34.2) | 140 (31.3) | ||
| Current | 96 (21.4) | 138 (30.8) | 0.002 | |
| Unknown | 5 | 5 | ||
| History of diabetes mellitus (%) | ||||
| No | 409 (95.6) | 397 (92.8) | ||
| Yes | 19 (4.4) | 31 (7.2) | 0.09 | |
| Unknown | 20 | 20 | ||
| Pepsinogen I, n (%) | ||||
| Low (<25) | 14 (3.2) | 20 (4.5) | ||
| High (≥25) | 427 (96.8) | 422 (95.5) | 0.29 | |
| Missing | 7 | 6 | ||
| Pepsinogen I/II, n (%) | ||||
| Low (<3) | 25 (5.7) | 28 (6.3) | ||
| High (>3) | 416 (94.3) | 414 (93.7) | 0.66 | |
| Missing | 7 | 6 | ||
| H. pylori, n (%) | ||||
| HP negative | 241 (53.9) | 250 (56.1) | ||
| HP positive | 206 (46.1) | 196 (44.0) | 0.50 | |
| Missing | 1 | 2 | ||
| CagA, n (%) | ||||
| CagA negative | 306 (68.9) | 302 (68.3) | ||
| CagA positive | 138 (31.1) | 140 (31.7) | 0.88 | |
| Missing | 4 | 6 | ||
1
Cases and control subjects were 1:1 matched on center, sex, age at blood collection (±3 years), date of blood donation (±3 months), time of blood donation (±2 h), and fasting status (<3h, 3–6h or >6 after the last meal).
2
P values were derived from paired t test for continuous variable, and from McNemar’s test or generalized McNemar’s test for categorical variables.